Identification of the protein-drug adduct formed between aldehyde dehydrogenase andS-methyl-N,N-diethylthiocarbamoyl sulfoxide by on-line proteolytic digestion high performance liquid chromatography electrospray ionization mass spectrometry

2000 ◽  
Vol 14 (10) ◽  
pp. 918-923 ◽  
Author(s):  
Maryann L. Shen ◽  
Kenneth L. Johnson ◽  
Dennis C. Mays ◽  
James J. Lipsky ◽  
Stephen Naylor
Keyword(s):  
Mass Spectrometry ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Electrospray Ionization ◽  
Aldehyde Dehydrogenase ◽  
High Performance ◽  
Ionization Mass ◽  
Protein Drug ◽  
Proteolytic Digestion ◽  
On Line

On-Line Coupling of High-Performance Liquid Chromatography to a Continuous-Flow Enzyme Assay Based on Electrospray Ionization Mass Spectrometry

2004 ◽  
Vol 76 (11) ◽  
pp. 3155-3161 ◽  
Author(s):  
Arjen R. de Boer ◽  
Thomas Letzel ◽  
Danny A. van Elswijk ◽  
Henk Lingeman ◽  
Wilfried M. A. Niessen ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Electrospray Ionization ◽  
Continuous Flow ◽  
High Performance ◽  
Enzyme Assay ◽  
Ionization Mass ◽  
On Line ◽  
Line Coupling
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